BI-2563 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division.
Related Prodcuts:
Tenovin-1; CHR-6494; LDN-192960; Epothilone D; Cladribine; VX-680; GW843682X; CYC-116; MK-1775; Entinostat