Clarithromycin

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Chemical Information

Product name：Clarithromycin	Purity：98% min
CAS NO：81103-11-9	Solubility：DMSO: ≥ 7.4 mg/mL
Molecular Formula：C₃₈H₆₉NO₁₃	Package：Package according to customer requirements
Molecular Weight：747.953	Storage：Store at -20℃

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Remarks

Clarithromycin is an antibiotic used to treat various bacterial infections. This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. Clarithromycin was developed in 1980. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Clarithromycin prevents bacteria by acting as a protein synthesis inhibitor. It binds to 23S rRNA, a component of the 50S subunit of the bacterial ribosome, thus inhibiting the translation of peptides.

Properties:
Appearance & Physical State: white to off-white crystalline powder
Density: 1.18 g/cm3
Melting Point: 217-220ºC
Boiling Point: 805.5ºC at 760 mmHg
Flash Point: 440.9ºC

P450 (e.g. CYP17) inhibitor Related Products:

Abiraterone; Abiraterone acetate; Ketoconazole; Orteronel(racemic); Orteronel; Galeterone; Cobicistat; Ozagrel; Ritonavir; Posaconazole; Voriconazole; Fluconazole

References

[1]. http://en.wikipedia.org/wiki/Clarithromycin

[2]. Niemi, M., P.J. Neuvonen, and K.T. Kivisto, The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide. Clin Pharmacol Ther, 2001. 70(1): p. 58-65.