Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.
Synonyms:
ozagrel;
p-(1-imidazolylmethyl)cinnamic acid;
Ozagrelum;
(E)-4-(1-imidazolylmethyl)cinnamic acid;
(E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2-propenic acid;
Cataclot (TN);
2-Propenoic acid,3-(4-(1H-imidazol-1-ylmethyl)phenyl)-,(E);
Properties:
Appearance & Physical State: white powder
Density: 1.17 g/cm3
Boiling Point: 468ºC at 760 mmHg
Melting Point: 223 - 224ºC
Flash Point: 236.8ºC
Refractive Index: 1.593
Prostaglandin Receptor Related Products:
E-7046; Ramatroban; Bimatoprost; Prostaglandin E2; Tafluprost; Carboprost; Treprostinil sodium; MRE-269; Travoprost; Misoprostol; Selexipag; Setipiprant