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TOK-001 Galeterone

TOK-001 Galeterone 851983-85-2
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Chemical Information
Product name:TOK-001 Galeterone Purity:98% min
CAS NO:851983-85-2 Solubility:DMSO : 18 mg/mL (46.33 mM)
Molecular Formula:C26H32N2O Package:Package according to customer requirements
Molecular Weight:388.545 Storage:Store at -20℃
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Galeterone, also known as TOK-001 and NX41765; is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an androgen receptor antagonist, 2) as a CYP17 lyase inhibitor and 3) by decreasing overall androgen receptor levels in prostate cancer tumors, all of which may result in a decrease in androgen-dependent growth signaling.

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