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AZD7762 860352-01-8
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Chemical Information
Product name:AZD7762 Purity:98% min
CAS NO:860352-01-8 Solubility:10 mM in DMSO
Molecular Formula:C17H20ClFN4O2S Package:Package according to customer requirements
Molecular Weight:398.883 Storage:Store at -20℃
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AZD-7762 is a synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemosensitizing activity. AZD7762 binds to and inhibits Chks, which may prevent cell cycle arrest and subsequent nucleotide excision repair in DNA-damaged tumor cells, resulting in tumor cell apoptosis. This agent may enhance the cytotoxicity of DNA-damaging agents. Chks are protein kinases that regulate either G1/S or G2/M transitions in the cell cycle. In the presence of DNA damage or incomplete DNA replication, Chks become activated and initiate cell cycle arrest to allow DNA repair or the completion of DNA replication.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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