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Product :

Tamibarotene

Tamibarotene 94497-51-5
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Chemical Information
Product name:Tamibarotene Purity:98% min
CAS NO:94497-51-5 Solubility:DMSO : 25.5 mg/mL (72.56 mM)
Molecular Formula:C22H25NO3 Package:Package according to customer requirements
Molecular Weight:351.439 Storage: Store at -20℃
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Remarks

Tamibarotene, also known as SY-1425, is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha/beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL-60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular retinoic acid binding protein (CRABP), tamibarotene may show sustained plasma levels compared to ATRA.

 

 

 

Retinoid Receptor inhibitor Related Products:

Fenretinide; Retinoic acid; Adapalene; Acitretin; Tazarotene; AM580; Bexarotene

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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