Vortioxetine, a novel antidepressant for the treatment of major depressive disorder, is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, 5-HT1B receptor partial agonist, 5-HT1A receptor agonist and serotonin (5-HT) transporter (SERT) inhibitor.
Vortioxetine hydrobromide is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
5-HT Receptor Inhibitors Related Products:
RS-127445; Asenapine Maleate; WAY-100635 Maleate; WAY-100635 maleate salt; Vortioxetine; Blonanserin; Intepirdine; Sertraline HCl; Lamotrigine; Azasetron hydrochloride; Iloperidone