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CUDC-101

CUDC-101 1012054-59-9
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Chemical Information
Product name:CUDC-101 Purity:98% min
CAS NO:1012054-59-9 Solubility:DMSO : 25 mg/mL (57.54 mM)
Molecular Formula:C24H26N4O4 Package:Package according to customer requirements
Molecular Weight:434.488 Storage:Store at -20℃
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Remarks

CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor tyrosine kinase (EGFR/ErbB1), and human epidermal growth factor receptor 2 tyrosine kinase (HER2/neu or ErbB2) with potential antineoplastic activity. HDAC/EGFR/HER2 inhibitor CUDC-101 inhibits the activity of these three enzymes but the exact mechanism of action is presently unknown. This agent may help overcome resistance to inhibition of EGFR and Her2 through a simultaneous, synergistic inhibition of EGFR, Her2, and HDAC.

 

 

 

 

HER2 Inhibitors Related Products:

Poziotinib (HM781-36B); Mubritinib; Tucatinib; Canertinib; Canertinib dihydrochloride; Lapatinib; Lapatinib ditosylate; Afatinib (BIBW2992); Afatinib (BIBW2992) Dimaleate; TAK-285; Sapitinib

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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