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Product :

SGI-1776

SGI-1776 1025065-69-3
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Chemical Information
Product name:SGI-1776 Purity:98% min
CAS NO:1025065-69-3 Solubility:DMSO : 125 mg/mL (308.32 mM; Need ultrasonic)
Molecular Formula:C20H22F3N5O Package:Package according to customer requirements
Molecular Weight:405.417 Storage:Store at -20℃
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Remarks

SGI-1776 is a small-molecule pan-Pim protein kinase inhibitor with potential antineoplastic activity. Pim kinase inhibitor SGI-1776 binds to and inhibits the activities of Pim-1, -2 and -3, serine-threonine kinases, which may result in the interruption of the G1/S phase cell cycle transition, the expression of pro-apoptotic Bcl2 proteins and tumor cell apoptosis. PIM kinases play key roles in cell cycle progression and apoptosis inhibition and may be overexpressed in various malignancies.

 

 

 

FLT3 Inhibitors Related Products:

Crenolanib; Dovitinib; FLX925; Quizartinib; Brigatinib; Pacritinib; Fedratinib; TG101209; Tandutinib; SU5614; Tamatinib; G-749

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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