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MK4827 Niraparib

MK4827 Niraparib 1038915-60-4
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Chemical Information
Product name:MK4827 Niraparib Purity:99% min
CAS NO:1038915-60-4 Solubility:DMSO : ≥ 32 mg/mL (99.88 mM)
Molecular Formula:C19H20N4O Package:Package according to customer requirements
Molecular Weight:320.388 Storage:Store at -20℃
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Niraparib, also known as MK4827, is an orally active, potent and selective poly(ADP-Ribose) polymerase (PARP) inhibitor that radiosensitizes human lung and breast cancer cells. Niraparib inhibits PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM respectively. Niraparib is currently in Phase 3 clinical trials for ovarian cancer and BRCA+ breast cancer.



Density: 1.34±0.1 g/cm3 (calc.)

Boiling Point: 463.6±45.0 °C (760 mmHg, calc.)

Flash Point: 234.188ºC




PARP Inhibitors Related Products:

Veliparib hcl; Olaparib; XAV-939; Rucaparib; Talazoparib; A-966492; PJ34 HCl; Pamiparib; WIKI4; G007-LK; AZD2461; Saroglitazar; Veliparib

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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