XAV-939 is a Tankyrase (TNKS) inhibitor with potential anticancer activity. XAV-939 antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV-939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells.
Properties:
Density: 1.5 g/cm3
Boiling Point: 429.3ºC at 760 mmHg
Flash Point: 213.4ºC
PARP Inhibitors Related Products:
Veliparib hcl; Olaparib; Rucaparib; Talazoparib; A-966492; PJ34 HCl; Niraparib; Pamiparib; WIKI4; G007-LK; AZD2461; Saroglitazar; Veliparib