Scopolamine hydrobromide

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Chemical Information

Product name：Scopolamine hydrobromide	Purity：98% min
CAS NO：114-49-8	Solubility：DMSO : ≥ 32 mg/mL (83.28 mM)
Molecular Formula：C₁₇H₂₂BrNO₄	Package：Package according to customer requirements
Molecular Weight：384.265	Storage：Store at -20℃

Quality control

Remarks

Scopolamine hydrobromide is a high affinity (nM) muscarinic antagonist. 5-HT3 receptor-responses are reversibly inhibited by Scopolamine with an IC50 of 2.09 μM.

Properties:
Appearance & Physical State: white crystalline solid powder
Boiling Point: 460.3ºC at 760 mmHg
Melting Point: 195-199ºC (dry matter)(lit.)
Vapor Pressure: 2.51E-10mmHg at 25°C

AChR Inhibitors Related Products:

Donepezil Hcl; (-)-Huperzine A; PNU-120596; Rivastigmine Tartrate; Darifenacin hydrobromide; Vinblastine sulfate; Tolterodine tartrate; Amfebutamone hydrochloride; Solifenacin; Solifenacin succinate; Trospium chloride; Pyridostigmine bromide; Varenicline; Revefenacin; Imidafenacin

References

[1]. Lochner M, et al. The muscarinic antagonists Scopolamine and atropine are competitive antagonists at 5-HT3 receptors. Neuropharmacology. 2016 Sep;108:220-8.

[2]. O ET, et al. COGNITIVE-ENHANCING PROPERTIES OF MORINDA LUCIDA (RUBIACEAE) AND PELTOPHORUM PTEROCARPUM (FABACEAE) IN SCOPOLAMINE-INDUCED AMNESIC MICE. Afr J Tradit Complement Altern Med. 2017 Mar 1;14(3):136-141.