Resminostat hydrochloride

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Chemical Information

Product name：Resminostat hydrochloride	Purity：98% min
CAS NO：1187075-34-8	Solubility：DMSO : ≥ 50 mg/mL (129.58 mM)
Molecular Formula：C₁₆H₂₀ClN₃O₄S	Package：Package according to customer requirements
Molecular Weight：385.866	Storage：Store at -20℃

Quality control

Remarks

Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC₅₀ values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC₅₀ of 877 nM.

Related Prodcuts:

Doxorubicin HCl; Epirubicin; Epirubicin HCl; Idarubicin HCl; Pirarubicin; Amrubicin; Amrubicin HCL; AMG 900; YK-4-279; AT-7519 HCL; Belinostat; Resminostat; Mizoribine; Daunorubicin hydrochloride

References

[1]. Mandl-Weber S, et al. The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells. Br J Haematol. 2010 May;149(4):518-28.

[2]. Enzenhofer E, et al. Effect of the histone deacetylase inhibitor resminostat on head and neck squamous cell carcinoma cell lines. Head Neck. 2017 May;39(5):900-907.