Epirubicin HCL

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Chemical Information

Product name：Epirubicin HCL	Purity：98% min
CAS NO：56390-09-1	Solubility：DMSO : ≥ 103.3 mg/mL (178.11 mM)
Molecular Formula：C₂₇H₃₀ClNO₁₁	Package：Packaging according to customer requirements
Molecular Weight：579.98	Storage：Store at -20℃

Quality control

COA

Remarks

Epirubicin hydrochloride is the hydrochloride salt of the 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.

Related Prodcuts:

Doxorubicin HCl; Epirubicin; Idarubicin HCl; Pirarubicin; Amrubicin; Amrubicin HCL; AMG 900; YK-4-279; AT-7519 HCL; Belinostat; Resminostat; Resminostat hydrochloride; Mizoribine;Daunorubicin hydrochloride

References

[1]. Cersosimo RJ, et al. Epirubicin: a review of the pharmacology, clinical activity, and adverse effects of an adriamycin analogue. J Clin Oncol. 1986 Mar;4(3):425-39.

[2]. Ozkan, A., et al. Epirubicin HCl toxicity in human-liver derived hepatoma G2 cells. Pol J Pharmacol, 2004. 56(4): p. 435-44.