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ABT-450 Paritaprevir

 ABT-450 Paritaprevir 1216941-48-8
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Chemical Information
Product name: ABT-450 Paritaprevir Purity:98% min
CAS NO:1216941-48-8 Solubility:10 mM in DMSO
Molecular Formula:C40H43N7O7S Package:Package according to customer requirements
Molecular Weight:765.877 Storage:Store at -20℃
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Remarks
Paritaprevir, also known as ABT-450 or Veruprevir, is an acylsulfonamide inhibitor of the NS3-4A serine protease manufactured by Abbott Laboratories that shows promising results as a treatment of hepatitis C. When given in combination with ritonavir and ribavirin for 12 weeks, the rate of sustained virologic response at 24 weeks after treatment has been estimated to be 95% for those with hepatitis C virus genotype 1. Resistance to treatment with paritaprevir is uncommon, because it targets the binding site, but has been seen to arise due to mutations at positions 155 and 168 in NS3.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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