Thiazovivin is a selective, cell-permeable small molecule that inhibits ROCK activity at a concentration 2 µM. Thiazovivin improves stemness maintenance of embryo-derived stem-like cells under chemically defined culture conditions in cattle. Thiazovivin directly targets Rho-associated kinase (ROCK) and increases expression of pluripotency factors. The process using thiazovivin could be easier, faster and more cost effective than transgene integration into somatic cells.
ROCK Inhibitors Related Products:
Y-27632 dihydrochloride; Y-27632; Fasudil HCl; GSK429286A; RKI-1447; Azaindole-1; Belumosudil (KD025); AT13148