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Y-27632 146986-50-7
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Chemical Information
Product name:Y-27632 Purity:98% min
CAS NO:146986-50-7 Solubility:DMSO : ≥ 32 mg/mL (129.38 mM)
Molecular Formula:C14H21N3O Package:Package according to customer requirements
Molecular Weight:247.336 Storage:Store at -20℃
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Y-27632 inhibits the ROCK family of kinases 100 times more potently than other kinases including protein kinase C, cAMP-dependent kinase and myosin light chain kinase. Y-27632 prolongs the lag time and delays the appearance of BrdU-labeled cells in a concentration-dependent manner, delays of about 1 and 4 h are noticed in the Swiss 3T3 cells treated with 10 and 100 μM Y-27632, respectively. Y-27632 promotes neuronal differentiation of adipose tissue-derived stem cells (ADSCs). Compared to 1.0 and 2.5 µM Y-27632 induced groups, percentages of neuroal-like cells achieved a peak in the 5.0 µM Y-27632 induced group.
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