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AG-490 Tyrphostin B42

AG-490 Tyrphostin B42 133550-30-8
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Chemical Information
Product name:AG-490 Tyrphostin B42 Purity:98% min
CAS NO:133550-30-8 Solubility:DMSO : ≥ 57 mg/mL (193.68 mM)
Molecular Formula:C17H14N2O3 Package:Package according to customer requirements
Molecular Weight:294.305 Storage:Store at -20℃
Quality control
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c-Kit+, Jak-2+ and non hematopoietic tumors c-Kit+, HER-2+, JAK-2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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