Febuxostat

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Chemical Information

Product name：Febuxostat	Purity：98% min
CAS NO：144060-53-7	Solubility：DMSO : 50 mg/mL (158.04 mM)
Molecular Formula：C₁₆H₁₆N₂O₃S	Package：Package according to customer requirements
Molecular Weight：316.375	Storage：Store at -20℃

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Remarks

Febuxostat, also known as Uloric and TMX-67, is a xanthine oxidase inhibitor used to treat hyperuricemia and chronic gout.

Properties:
Appearance & Physical State: Crystalline Solid
Density: 1.31 g/cm3
Melting Point: 238-239ºC
Boiling Point: 536.6ºC at 760 mmHg
Flash Point: 278.3ºC
Refractive Index: 1.605
Vapor Pressure: 2.41E-12mmHg at 25°C

ROS Related Products:

Allopurinol; Setanaxib; Vandetanib; BI-D1870; BAY 87-2243; Piperlongumine

References

[1]. Takano Y, et al. Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life Sci, 2005, 76(16), 1835-1847.

[2]. Sánchez-Lozada LG, et al. Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome. Am J Physiol Renal Physiol, 2008, 294(4), F710-F718.

[3]. Sánchez-Lozada LG, et al. Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia. Nephron Physiol, 2008, 108(4), p69-p78.