Piperlongumine Piplartine

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：Piperlongumine Piplartine	Purity：98% min
CAS NO：20069-09-4	Solubility：DMSO : 125 mg/mL (393.90 mM)
Molecular Formula：C₂₇H₃₁N₇O₂	Package：Package according to customer requirements
Molecular Weight：317.336	Storage：Store at -20℃

Quality control

Remarks

Piperlongumine , also known as Piplartine , is a biologically active alkaloid/amide from peppers, as from long pepper (Piper longum L. - Piperaceae). Long pepper is one of the most widely used in Ayurvedic medicine, which is used to treat many diseases, including tumors. The reported pharmacological activities of piplartine include cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, and schistosomicidal activities. Among the multiple pharmacological effects of piplartine, its anticancer property is the most promising.

Properties:

Density: 1.223g/cm3

Boiling Point: 475.6ºC at 760mmHg

Melting Point: 124ºC

Flash Point: 241.4ºC

ROS Related Products:

Allopurinol; Setanaxib; Vandetanib; BI-D1870; BAY 87-2243; Febuxostat

References

[1]. Karki K, et al. Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors.

[2]. Wu X, e,t al. Piperlongumine inhibits angiotensin II-induced extracellular matrix expression in cardiac fibroblasts. J Cell Biochem. 2018 Dec;119(12):10358-10364