Pitavastatin calcium

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Chemical Information

Product name：Pitavastatin calcium	Purity：98% min
CAS NO：147526-32-7	Solubility：DMSO : ≥ 50 mg/mL (113.51 mM)
Molecular Formula：C₅₀H₄₆CaF₂N₂O₈	Package：Package according to customer requirements
Molecular Weight：880.984	Storage：Store at -20℃

Quality control

COA

Remarks

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting Nox. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187.

Properties:

Appearance & Physical State: white to off-white powder

Boiling Point: 692ºC at 760 mmHg

Flash Point: 372.3ºC

HMG-CoA Reductase Inhibitors Related Prodcuts:

Simvastatin; Rosuvastatin calcium; Lovastatin; Simvastatin ammonium salt; Rosuvastatin; Rosuvastatin Sodium; Rosuvastatin ethyl ester; Pitavastatin; Pravastatin Sodium

References

[1]. Mukhtar RY, et al. Pitavastatin. Int J Clin Pract. 2005 Feb;59(2):239-52.

[2]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.