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Marimastat 154039-60-8
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Chemical Information
Product name:Marimastat Purity:98% min
CAS NO:154039-60-8 Solubility:Soluble in DMSO, not in water
Molecular Formula:C15H29N3O5 Package:Package according to customer requirements
Molecular Weight:331.41 Storage:Store at -20℃
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Marimastat, aslo known as BB-2516 and TA-2516, is an orally-active synthetic hydroxamate and inhibitor of matrix metalloproteinases with potential antineoplastic activity. Marimastat covalently binds to the zinc(II) ion in the active site of matrix metalloproteinases (MMPs), thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent may also inhibit tumor necrosis factor-alpha converting enzyme (TACE), an enzyme involved in tumor necrosis factor alpha (TNF-alpha) production that may play a role in some malignancies as well as in the development of arthritis and sepsis.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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