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T-5224

T-5224 530141-72-1
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Chemical Information
Product name:T-5224 Purity:98% min
CAS NO:530141-72-1 Solubility:DMSO : ≥ 31 mg/mL (59.90 mM)
Molecular Formula:C29H27NO8 Package:Package according to customer requirements
Molecular Weight:517.527 Storage:Store at -20℃
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Remarks

T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation.


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