Lasofoxifene Tartrate

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Chemical Information

Product name：Lasofoxifene Tartrate	Purity：99% min
CAS NO：190791-29-8	Solubility：DMSO : 6 mg/mL (10.65 mM)
Molecular Formula：C₂₈H₃₂ClNO₂	Package：Package according to customer requirements
Molecular Weight：450.012	Storage：2-8°C

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Remarks

Lasofoxifene Tartrate is a third-generation, non-steroidal selective estrogen receptor modulator (SERM) which binds with high affinity to the human estrogen receptor-α with IC50 value of 1.5 nM.

Properties:
Boiling Point: 572.4ºC at 760 mmHg
Flash Point: 300ºC
Vapor Pressure: 1.05E-13mmHg at 25°C

Estrogen/progestogen Receptor Inhibitors Related Products:

Fulvestrant; Raloxifene hydrochloride; Brilanestrant; Tamoxifen; Tamoxifen citrate; Dienogest; Drospirenone; Ulipristal acetate; Megestrol Acetate; Pregnenolone; Estriol; Estrone; Bazedoxifene Acetate; Endoxifen HCl; Ospemifene ; AZD9496

References

[1]. Andersson A, et al. Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis. Rheumatology (Oxford). 2015 Sep 30. pii: kev355.