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Sorafenib 284461-73-0
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Chemical Information
Product name:Sorafenib Purity:98% min
CAS NO:284461-73-0 Solubility:DMSO: ≥ 45 mg/mL
Molecular Formula:C21H16ClF3N4O3 Package:Package according to customer requirements
Molecular Weight:464.825 Storage:Store at -20℃
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Sorafenib is a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Sorafenib was approved in 2005 for use in the treatment of advanced renal cancer.

Appearance & Physical State: White to off-white solid
Density: 1.454 g/cm3
Melting Point: 225-235ºC
Boiling Point: 523.3ºC at 760 mmHg
Flash Point: 270.3ºC
Vapor Pressure: 4.76E-11mmHg at 25°C

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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