Y-320

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Chemical Information

Product name：Y-320	Purity：98% min
CAS NO：288250-47-5	Solubility：DMSO : 5.5 mg/mL (10.89 mM)
Molecular Formula：C₂₇H₂₉ClN₆O₂	Package：Package according to customer requirements
Molecular Weight：505.011	Storage：Store at 2-8°C

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Remarks

Y-320 is an orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.

Chemical Name:

1-(4-chlorophenyl)-N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide

Synonyms:

1-(4-Chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-carboxamide;

Properties:

Boiling point: 631.2±55.0 °C(Predicted)

density: 1.34±0.1 g/cm3(Predicted)

pka: 11.82±0.70(Predicted)

Immunology & Inflammation related Inhibitors Related Prodcuts:

Pimecrolimus; Cyclosporin A; Bestatin; GI254023X; Bindarit; TAPI-1; Avadomide; Thymopentin; Pranlukast; Laquinimod; VGX-1027; Imiquimod; Levamisole hydrochloride; Halcinonide; Sodium gualenate; Aceclofenac; Fenoprofen calcium; Pidotimod; Etofenamate; Tenoxicam

References

[1]. Ushio H, et al. A new phenylpyrazoleanilide, y-320, inhibits interleukin 17 production and ameliorates collagen-induced arthritis in mice and cynomolgus monkeys. Pharmaceuticals (Basel). 2013 Dec 23;7(1):1-17.