Etofenamate TVX485

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Chemical Information

Product name：Etofenamate TVX485	Purity：98% min
CAS NO：30544-47-9	Solubility：DMSO : ≥ 50 mg/mL (135.38 mM)
Molecular Formula：C₁₈H₁₈F₃NO₄	Package：Package according to customer requirements
Molecular Weight：369.335	Storage：Store at -20℃

Quality control

Remarks

Etofenamate, also known as TVX485 and WHR-5020, is a non-steroidal anti-inflammatory drug used for the treatment of joint and muscular pain. The Etofenamate gel ( 5.0% (w/w) ) with 30% ethanol showed in vivo anti-inflammatory activity with suitable physical chemical and microbiologic characteristics. In vitro release and permeation studies revealed that the different amounts of ethanol used influenced the release profiles of etofenamate. Moreover, it was demonstrated that this formulation is an adequate vehicle for the etofenamate skin permeation.

Properties:

Density: 1.317g/cm3

Boiling Point: 451.1ºC at 760 mmHg

Flash Point: 226.6ºC

Refractive Index: 1.552

Immunology & Inflammation related Inhibitors Related Prodcuts:

Pimecrolimus; Cyclosporin A; Bestatin; GI254023X; Bindarit; TAPI-1; Avadomide; Thymopentin; Pranlukast; Laquinimod; VGX-1027; Y-320; Imiquimod; Levamisole hydrochloride; Halcinonide; Sodium gualenate; Aceclofenac; Fenoprofen calcium; Pidotimod; Tenoxicam

References

[1]. Bender T, Bariska J, Rojkovich B, Bálint G. Etofenamate levels in human serum and synovial fluid following iontophoresis. Arzneimittelforschung. 2001;51(6):489-92.

[2]. Fraga A, de Almeida M, Moreira-da-Silva V et al. Intramuscular Etofenamate versus Diclofenac in the Relief of Renal Colic : A Randomised, Single-Blind, Comparative Study. Clin Drug Investig. 2003;23(11):701-6.