Fluprostenol Travoprost acid

Fluprostenol, (+)-, is an analog of Prostaglandin F2α with potent FP receptor agonist activity.A metabolically stable analog of Prostaglandin F2α with potent FP receptor agonist activity. An impurity of Travoprost.

Fluprostenol is a metabolically stable analog of PGF2α with potent FP receptor agonist activity. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. Fluprostenol inhibits PGF2α binding to human and rat FP receptors with IC50 values of 3.5 and 7.5 nM, respectively. It is a much more potent luteolytic agent than PGF2α in rats with a minimum fully effective dose of 270 μg/kg to terminate pregnancy. It is also an effective inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 of 3-10 x 10?11 M.

Chemical Name:

[3H]-Travoprost acid

Synonyms:

(+)-FLUPROSTENOL;

Travoprost Acid;

Fluprostenol;

Related Prodcuts:  (+)-Cloprostenol; Cloprostenol; Misoprostol; Carboprost; Tafluprost; Dinoprostone; Dinoprost; Trometamol; Alprostadil; Iloprost; Limaprost; Bimatoprost; Latanoprost; Lubiprostone; 15-keto Travoprost; 15S-Travoprost; 5,6-trans Travoprost; Travoprost 

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