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Limaprost 74397-12-9
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Chemical Information
Product name:Limaprost Purity:99% min
CAS NO:74397-12-9 Solubility:DMSO : ≥ 40 mg/mL (105.12 mM)
Molecular Formula:C22H36O5 Package:Packaging according to customer requirements
Molecular Weight:380.52 Storage:Store at -20℃
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Limaprost(OP1206) is a PGE1 analog and potent platelet adhesion inhibitor. Target: Others Limaprost, an alprostadil (prostaglandin E1) analogue, is a vasodilator that increases blood flow and inhibits platelet aggregation. Limaprost is a n analog of PGE1 with structural modifications intended to give a prolonged half-life and greater potency. It is orally active in both guinea pigs and rats at doses of 100 mg/kg as an inhibitor of ADP and collagen induced platelet aggregation. It is 10-1,000 times more potent than PGE1 as a platelet adhesive inhibitor, measured in vitro. Intra-coronary injection (100 ng/kg) or intravenous injection (3 mg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 mg/kg orally in rats.




Related Prodcuts: 

Latanoprost Lactol; trans-(15S)-Latanoprost; Latanoprostene bunod; 15(S)-Latanoprost; trans-Latanoprost(+)-Cloprostenol; Cloprostenol; Misoprostol; Carboprost; Tafluprost; Dinoprostone; Dinoprost; Trometamol; Alprostadil; Bimatoprost; (+/-)-Corey lactone diol; Beraprost sodium; Limaprost Alfadex N-2; Dehydrate limaprost

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