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Latanoprostene bunod

Latanoprostene bunod 860005-21-6
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Chemical Information
Product name:Latanoprostene bunod Purity:98%min
CAS NO:860005-21-6 Solubility:Soluble in DMSO
Molecular Formula:C27H41NO8 Package:Packaging according to customer requirements
Molecular Weight:507.62 Storage:Store at -20℃
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Remarks
PF-3187207 is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity. It loweres intraocular pressure (IOP) more effectively than latanoprost in monkeys, dogs and rabbits.
References

1: Lu LJ, Tsai JC, Liu J. Novel Pharmacologic Candidates for Treatment of Primary Open-Angle Glaucoma. Yale J Biol Med. 2017 Mar 29;90(1):111-118. eCollection 2017 Mar. Review. PubMed PMID: 28356898; PubMed Central PMCID: PMC5369028.

2: Kaufman PL. Latanoprostene bunod ophthalmic solution 0.024% for IOP lowering in glaucoma and ocular hypertension. Expert Opin Pharmacother. 2017 Mar;18(4):433-444. doi: 10.1080/14656566.2017.1293654. Epub 2017 Feb 20. Review. PubMed PMID: 28234563; PubMed Central PMCID: PMC5595251

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