PF-3187207 Latanoprostene bunod

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Chemical Information

Product name：PF-3187207 Latanoprostene bunod	Purity：99% min
CAS NO：860005-21-6	Solubility：DMSO : 250 mg/mL (492.49 mM)
Molecular Formula：C₂₇H₄₁NO₈	Package：Packaging according to customer requirements
Molecular Weight：507.62	Storage：Store at -20℃

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COA

Remarks

Latanoprostene bunod is a a nitric oxide (NO)-donating latanoprost with prostaglandin activity. It loweres intraocular pressure (IOP) more effectively than latanoprost in monkeys, dogs and rabbits.

Related Prodcuts:

Latanoprost Lactol; trans-(15S)-Latanoprost; Latanoprost; 15(S)-Latanoprost; trans-Latanoprost; Cloprostenol; Misoprostol; Carboprost; Tafluprost; Dinoprostone; Dinoprost; Trometamol; Alprostadil; Iloprost; Limaprost; Bimatoprost; Lubiprostone

References

1: Lu LJ, Tsai JC, Liu J. Novel Pharmacologic Candidates for Treatment of Primary Open-Angle Glaucoma. Yale J Biol Med. 2017 Mar 29;90(1):111-118. eCollection 2017 Mar. Review. PubMed PMID: 28356898; PubMed Central PMCID: PMC5369028.

2: Kaufman PL. Latanoprostene bunod ophthalmic solution 0.024% for IOP lowering in glaucoma and ocular hypertension. Expert Opin Pharmacother. 2017 Mar;18(4):433-444. doi: 10.1080/14656566.2017.1293654. Epub 2017 Feb 20. Review. PubMed PMID: 28234563; PubMed Central PMCID: PMC5595251