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MGCD0103 Mocetinostat

MGCD0103 Mocetinostat 726169-73-9
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Chemical Information
Product name:MGCD0103 Mocetinostat Purity:98% min
CAS NO:726169-73-9 Solubility:DMSO : 50 mg/mL (126.12 mM; Need ultrasonic)
Molecular Formula:C23H20N6O Package:Package according to customer requirements
Molecular Weight:396.445 Storage:Store at -20℃
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Remarks

Mocetinostat, also known as MGCD-0103, is a rationally designed, orally available, Class 1-selective, small molecule, 2-aminobenzamide HDAC inhibitor with potential antineoplastic activity. Mocetinostat binds to and inhibits Class 1 isoforms of HDAC, specifically HDAC 1, 2 and 3, which may result in epigenetic changes in tumor cells and so tumor cell death; although the exact mechanism has yet to be defined, tumor cell death may occur through the induction of apoptosis, differentiation, cell cycle arrest, inhibition of DNA repair, upregulation of tumor suppressors, down regulation of growth factors, oxidative stress, and autophagy, among others.

 

 

 

HDAC Inhibitors Related Prodcuts:

Dacinostat; Belinostat; Tacedinaline; RoMidepsin; Givinostat; Vorinostat; Tubastatin A HCl; Entinostat; Panobinostat; Trichostatin A; Pracinostat; AR-42; Ricolinostat; WT161; ACY-738; Tasquinimod; Domatinostat; LMK-235; BRD3308

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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