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Product :

SB939 Pracinostat

SB939 Pracinostat 929016-96-6
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Chemical Information
Product name:SB939 Pracinostat Purity:98% min
CAS NO:929016-96-6 Solubility:10 mM in DMSO
Molecular Formula:C20H30N4O2 Package:Package according to customer requirements
Molecular Weight:358.478 Storage:Store at -20℃
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Remarks

Pracinostat, also known as SB939, is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. In March 2014, pracinostat has granted Orphan Drug for acute myelocytic leukemia (AML) and for the treatment of T-cell lymphoma by the Food and Drug Administration.


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