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|Product name：OSU-03012 AR-12
||Solubility：10 mM in DMSO
||Package：Package according to customer requirements
||Storage：Store at -20℃
OSU03012; also known as AR12, is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. AR-12 may also cause cell death through the induction of stress in the endoplasmic reticulum. We are currently conducting a multi-centered Phase I clinical study of AR-12 in adult patients with advanced or recurrent solid tumors or lymphoma.
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 Yacoub A, et al. Mol Pharmacol, 2006, 70(2), 589-603.
 Porchia LM, et al. Mol Pharmacol, 2007, 72(5), 1124-1131.