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OSI-027

OSI-027 936890-98-1
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Chemical Information
Product name:OSI-027 Purity:98% min
CAS NO:936890-98-1 Solubility:Soluble in DMSO
Molecular Formula:C21H22N6O3 Package:Package according to customer requirements
Molecular Weight:406.438 Storage:Store at -20℃
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Remarks

 OSI-027 is an orally bioavailable mammalian target of rapamycin (mTOR) kinase inhibitor with potential antineoplastic activity. mTOR kinase inhibitor OSI-027 binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR is a serine/threonine kinase that is upregulated in some tumors and plays an important role downstream in the PI3K/Akt/mTOR signaling pathway. Check for active clinical trials or closed clinical trials using this agent. 

 

 

Related Prodcuts:

Tacrolimus; AZD8055; AZD8055 fumarate; Vistusertib; Zotarolimus; XL388; INK 128; PP121; Desmethyl-VS-5584; AZD-8055

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