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BMS777607

BMS777607 1025720-94-8
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Chemical Information
Product name:BMS777607 Purity:98% min
CAS NO:1025720-94-8 Solubility:DMSO: ≥ 39 mg/mL
Molecular Formula:C25H19ClF2N4O4 Package:Package according to customer requirements
Molecular Weight:512.8930 Storage:Store at -20℃
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Remarks

BMS-777607, also known as BMS-817378 and ASLAN-002, a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.

 

 

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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