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BMS777607

BMS777607 1025720-94-8
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Chemical Information
Product name:BMS777607 Purity:98% min
CAS NO:1025720-94-8 Solubility:DMSO: ≥ 39 mg/mL
Molecular Formula:C25H19ClF2N4O4 Package:Package according to customer requirements
Molecular Weight:512.8930 Storage:Store at -20℃
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Remarks
BMS-777607, also known as BMS-817378 and ASLAN-002, a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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