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Tivantinib

Tivantinib 905854-02-6
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Chemical Information
Product name:Tivantinib Purity:98% min
CAS NO:905854-02-6 Solubility:10 mM in DMSO
Molecular Formula:C23H19N3O2 Package:Protein Tyrosine Kinase/RTK
Molecular Weight:369.416 Storage:Store at -20℃
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Remarks
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity. c-Met inhibitor ARQ 197 binds to the c-Met protein and disrupts c-Met signal transduction pathways, which may induce cell death in tumor cells overexpressing c-Met protein or expressing consitutively activated c-Met protein. c-Met protein, the product of the proto-oncogene c-Met, is a receptor tyrosine kinase also known as hepatocyte growth factor receptor (HGFR); this protein is overexpressed or mutated in many tumor cell types and plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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