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Product :

RVX-208 Apabetalone

RVX-208 Apabetalone 1044870-39-4
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Chemical Information
Product name:RVX-208 Apabetalone Purity:99% min
CAS NO:1044870-39-4 Solubility:DMSO : ≥ 33 mg/mL (89.09 mM)
Molecular Formula:C20H22N2O5 Package:Package according to customer requirements
Molecular Weight:370.399 Storage:Store at -20℃
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Remarks

Apabetalone, also known as RVX-208, is a potent inhibitor of BET bromodomains. RVX-208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX-208 increases the production of ApoA-I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL-C, but the molecular target was not previously reported. RVX-208 may be a promising new approach to the treatment of atherosclerosis.

 

Chemical Properties:

Boiling point: 594.2±60.0 °C(Predicted)

density: 1.28±0.1 g/cm3(Predicted)

pka: 14.21±0.10(Predicted)

 

 

 

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ICG-001; (+)-JQ1; I-BET151; PFI-1; Molibresib; C646; Curcumin; Bromosporine; Birabresib; UNC1215; GSK6853; CPI-637; BI-9564; PFI-4; XMD8-92; MS436; CPI-203; KG-501; Mivebresib; GSK2801

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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