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PRI-724 ICG001 isomer

PRI-724 ICG001 isomer 847591-62-2
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Chemical Information
Product name:PRI-724 ICG001 isomer Purity:98% min
CAS NO:847591-62-2 Solubility:DMSO
Molecular Formula:C33H32N4O4 Package:Package according to customer requirements
Molecular Weight:548.632 Storage:Store at -20℃
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PRI-724, an isomer or enantiomer of ICG-001, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP (the binding protein of the cAMP response element-binding protein CREB); together with other transcription factors beta-catenin/CBP binds to WRE (Wnt-responsive element) and activates transcription of a wide range of target genes of Wnt/beta-catenin signaling. Note: ICG-001 and PRR-724 are not the same molecule, which are enantiomer isomers. Many vendors confused them.
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