Larotrectinib sulfate (LOXO-101, ARRY-470) is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.
Trk receptor Inhibitors Related Products:
SP600125; Danusertib; GW441756; Altiratinib; GNF-5837; Ropotrectinib; Entrectinib; ANA-12