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DCC-2701 Altiratinib

DCC-2701 Altiratinib 1345847-93-9
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Chemical Information
Product name:DCC-2701 Altiratinib Purity:99.0% min
CAS NO:1345847-93-9 Solubility:DMSO : ≥ 33 mg/mL (64.65 mM)
Molecular Formula:C26H21F3N4O4 Package:Package according to customer requirements
Molecular Weight:510.465 Storage:Store at -20℃
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Remarks

Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF.

 

 

 

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LY2874455; ZM-306416; ZM323881; Tyrphostin A9; Orantinib; Brivanib; Foretinib; SU5402; Semaxanib; SAR131675; Lucitanib; Apatinib; SKLB610; SGI-7079; AZD2932

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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