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Product :

AZD2932

AZD2932 883986-34-3
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Chemical Information
Product name:AZD2932 Purity:98% min
CAS NO:883986-34-3 Solubility:Soluble in DMSO, not in water
Molecular Formula:C24H25N5O4 Package:Package according to customer requirements
Molecular Weight:447.49 Storage:Store at -20℃
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Remarks
AZD2932 effectively inhibits the activities of VEGFR-2 (IC50, 8 nM), PDGFRβ (IC50,4 nM), Flt-3 (IC50, 7 nM), and c-Kit (IC50, 9 nM). AZD2932 inhibits both PDGFRα and PDGFRβ phosphorylation with a correlation close to 1:1. AZD2932 does not inhibit the various cytochrome P450 isoforms with the worst IC50 being against 2C9 (8.0 μM). AZD2932 has no activity against hERG (IC50, 137 μM).
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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