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ZM323881

ZM323881 193001-14-8
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Chemical Information
Product name:ZM323881 Purity:98% min
CAS NO:193001-14-8 Solubility:10 mM in DMSO
Molecular Formula:C22H18FN3O2 Package:Package according to customer requirements
Molecular Weight:375.396 Storage:Store at -20℃
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Remarks
ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro.
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