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Foretinib GSK1363089

Foretinib GSK1363089 849217-64-7
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Chemical Information
Product name:Foretinib GSK1363089 Purity:98% min
CAS NO:849217-64-7 Solubility:DMSO : ≥ 38 mg/mL (60.06 mM)
Molecular Formula:C34H34F2N4O6 Package:Package according to customer requirements
Molecular Weight:632.654 Storage:Store at -20℃
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Remarks
Foretinib, also known as XL880 and GSK1363089, is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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