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SKLB610

SKLB610 1125780-41-7
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Chemical Information
Product name:SKLB610 Purity:98% min
CAS NO:1125780-41-7 Solubility:DMSO: 83 mg/mL (199.82 mM)
Molecular Formula:C21H16F3N3O3 Package:Package according to customer requirements
Molecular Weight:415.365 Storage:Store at -20℃
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Remarks

SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibited angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth factor receptor 2 (FGFR2) and platelet-derived growth factor receptor (PDGFR) at rate of 97%, 65% and 55%, respectively, at concentration of 10μM in biochemical kinase assays. SKLB610 exhibited its antitumor activity as a multi-targeted inhibitor with more potent inhibition of VEGFR2 activity. Its potential to be a candidate of anticancer agent is worth being further investigated.

 

 

 

 

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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