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LY2874455 1254473-64-7
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Chemical Information
Product name:LY2874455 Purity:98% min
CAS NO:1254473-64-7 Solubility:DMSO : 50 mg/mL (112.53 mM)
Molecular Formula:C21H19Cl2N5O2 Package:Package according to customer requirements.
Molecular Weight:444.314 Storage:Store at -20℃
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LY2874455 is a novel and potent FGF/FGFR Inhibitor. It exhibits a potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship.




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[1] Zhao G, et al. Mol Cancer Ther. 2011, 10(11), 2200-2210.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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