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Product :

SU5416 Semaxanib

SU5416 Semaxanib 204005-46-9
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Chemical Information
Product name:SU5416 Semaxanib Purity:98% min
CAS NO:204005-46-9 Solubility:DMSO : 22.5 mg/mL (94.43 mM); H2O : < 0.1 mg/mL
Molecular Formula:C15H14N2O Package:Package according to customer requirements
Molecular Weight:238.284 Storage:Store at -20℃
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Remarks

Semaxanib, also known as SU5416, is a quinolone derivative with potential antineoplastic activity. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2), which may inhibit VEGF-stimulated endothelial cell migration and proliferation and reduce the tumor microvasculature. This agent also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells.

 

 

 

Related Prodcuts:

LY2874455; ZM-306416; ZM323881; Tyrphostin A9; Orantinib; Brivanib; Foretinib; SU5402; SAR131675; Lucitanib; Apatinib; SKLB610; Altiratinib; SGI-7079; AZD2932

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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