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TPX-0005 Ropotrectinib

TPX-0005 Ropotrectinib 1802220-02-5
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Chemical Information
Product name:TPX-0005 Ropotrectinib Purity:99% min
CAS NO:1802220-02-5 Solubility:DMSO : ≥ 83.3 mg/mL (234.40 mM)
Molecular Formula:C18H18FN5O2 Package:Packaging according to customer requirements
Molecular Weight:355.3734 Storage:Store at -20℃
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Ropotrectinib, also known as TPX-0005, is a potent ALK/ROS-1/TRK inhibitor. TPX-0005 plus EGFR TKI suppressed expression and activation of RTKs and downstream signaling intermediates. Co-expression of CDCP1 and AXL is often observed in EGFR-mutation-positive tumors, limiting the efficacy of EGFR TKIs. Co-treatment with EGFR TKI and TPX-0005 warrants testing.



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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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