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Product :

PP1 AGL 1872

PP1 AGL 1872 172889-26-8
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Chemical Information
Product name:PP1 AGL 1872 Purity:98% min
CAS NO:172889-26-8 Solubility:DMSO : 28 mg/mL (99.52 mM)
Molecular Formula:C16H19N5 Package:Package according to customer requirements
Molecular Weight:281.356 Storage:Store at -20℃
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Remarks

PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. PP1 effectively blocks TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells. PP1 blocks TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors. PP1 was also found to potentiate tumor-suppressive effect of connexin 32 gene in renal cancer cells.

 

Synonyms:

1-(tert-Butyl)-3-(p-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;

1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine;

4-Amino-5-(methylphenyl)-7-(t-butyl)pyrazolo-(3,4-d)pyrimidine;

1H-Pyrazolo[3,4-d]pyrimidin-4-amine (1-(1,1-dimethylethyl)-3-(4-methylphenyl);

 

Properties:

Appearance & Physical State: Off-white to grey solid

Density: 1.23g/cm3

Boiling Point: 478.8ºC at 760 mmHg

Melting Point: 205-207ºC

Flash Point: 243.4ºC

Refractive Index: 1.652

Vapor Pressure: 2.49E-09mmHg at 25°C

 

 

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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