Lomustine is a nitrosourea with antineoplastic activity. Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Properties:
Appearance & Physical State: Yellow powder.
Density: 1.35 g/cm3
Melting Point: 88-90ºC
Refractive Index: 1.57
Vapor Pressure: 0.00142mmHg at 25°C
Related Products:
Pritelivir mesylate; Capecitabine; Nimustine hydrochloride; Thiotepa; KU-55933; Ganetespib; Onalespib; INNO-206 HCl salt; Aldoxorubicin; Pritelivir