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Product :

STA-9090 Ganetespib

STA-9090 Ganetespib 888216-25-9
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Chemical Information
Product name:STA-9090 Ganetespib Purity:98% min
CAS NO:888216-25-9 Solubility:DMSO: ≥ 32 mg/mL
Molecular Formula:C20H20N4O3 Package:Package according to customer requirements
Molecular Weight:364.398 Storage:Store at -20℃
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Remarks
Ganetespib, also known as STA-9090, is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor STA-9090 binds to and inhibits Hsp90, resulting in the proteasomal degradation of oncogenic client proteins, the inhibition of cell proliferation and the elevation of heat shock protein 72 (Hsp72); it may inhibit the activity of multiple kinases, such as c-Kit, EGFR, and Bcr-Abl, which as client proteins depend on functional HsP90 for maintenance.

 

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